Endocrine Abstracts

It has been suggested that the association between osteoporosis and cardio-vascular diseases is not just due to the aging process. The osteoprotegerin (OPG)/RANKL system has been identified as a possible mediator of arterial calcification suggesting common links between osteoporosis and vascular diseases. Moreover, breast arterial calcification (BAC) is reported to be associated with an increased prevalence of both cardiovascular risk factors and cardiovascular morbidity. In c...

Introduction: Recent reports showed that 2–9.4% of diabetic patients have Cushing’s syndrome (CS) including its mild form, subclinical CS (subCS), but there is no report about screening of acromegaly in diabetic patients. Either 1-mg or 0.5-mg dexamethasone suppression test (DST) is used as the screening test of adrenal CS or Cushing’s disease (CD). The aim of the present study was to screen CS including CD and acromegaly in Japanese diabetic patients.<p cla...

Introduction: It has been reported that primary aldosteronism(PA) is often associated with subclinical Cushing syndrome (SCS). In the present study, we investigated the frequency of SCS in subjects with PA.Method: Subjects included consecutive patients (n=43) who were diagnosed as PA between 2003 and 2011 in our institute. They were screened by plasma renin activity (PRA (ng/ml/h)) plasma aldosterone concentration (PAC (pg/mL)) ratio (ARR) above 2...